F067-1161 Screening compound: 3-(3-fluorophenyl)-4-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-N-(propan-2-yl)-3,4-dihydroquinazoline-7-carboxamide

F067-1161 Screening compound: 3-(3-fluorophenyl)-4-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-N-(propan-2-yl)-3,4-dihydroquinazoline-7-carboxamide
F067-1161 Screening compound: 3-(3-fluorophenyl)-4-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-N-(propan-2-yl)-3,4-dihydroquinazoline-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F067-1161
3-(3-fluorophenyl)-4-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-N-(propan-2-yl)-3,4-dihydroquinazoline-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F067-1161

Molecular Formula

C26H22FN3O3S (C26 H22 FN3 O3 S)

Compound Name

3-(3-fluorophenyl)-4-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-N-(propan-2-yl)-3,4-dihydroquinazoline-7-carboxamide

IUPAC name

3-(3-fluorophenyl)-4-oxo-2-[(2-oxo-2-phenylethyl)sulfanyl]-N-(propan-2-yl)-34-dihydroquinazoline-7-carboxamide

SMILES

CC(C)NC(c(cc1)cc(N=C(N2c3cc(F)ccc3)SCC(c3ccccc3)=O)c1C2=O)=O

InChI

InChI=1S/C26H22FN3O3S/c1-16(2)28-24(32)18-11-12-21-22(13-18)29-26(34-15-23(31)17-7-4-3-5-8-17)30(25(21)33)20-10-6-9-19(27)14-20/h3-14,16H,15H2,1-2H3,(H,28,32)

InChI Key

FNGWJDTYBAASMG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14939394

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

475.54

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.644

Distribution Coefficient, logD

3.644

Water Solubility, LogSw

-4.10

Polar Surface Area

62.066

Acid Dissociation Constant (pKa)

13.76

Base Dissociation Constant (pKb)

3.53

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

15.40

F067-1161 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

PI3K-Targeted Library (17255 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with F067-1161 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F067-1161?
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What is the minimum amount of F067-1161 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F067-1161
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F067-1161
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F067-1161 available by request