F067-1439 Screening compound: 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-N-cyclopentyl-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide

F067-1439 Screening compound: 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-N-cyclopentyl-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide
F067-1439 Screening compound: 2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-N-cyclopentyl-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F067-1439
2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-N-cyclopentyl-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F067-1439

Molecular Formula

C28H23ClFN3O3S (C28 H23 ClFN3 O3 S)

Compound Name

2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-N-cyclopentyl-3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide

IUPAC name

2-{[2-(4-chlorophenyl)-2-oxoethyl]sulfanyl}-N-cyclopentyl-3-(4-fluorophenyl)-4-oxo-34-dihydroquinazoline-7-carboxamide

SMILES

O=C(CSC(N1c(cc2)ccc2F)=Nc(cc(cc2)C(NC3CCCC3)=O)c2C1=O)c(cc1)ccc1Cl

InChI

InChI=1S/C28H23ClFN3O3S/c29-19-8-5-17(6-9-19)25(34)16-37-28-32-24-15-18(26(35)31-21-3-1-2-4-21)7-14-23(24)27(36)33(28)22-12-10-20(30)11-13-22/h5-15,21H,1-4,16H2,(H,31,35)

InChI Key

BJQLCAMZKQHBPT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14939580

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

536.03

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.021

Distribution Coefficient, logD

5.020

Water Solubility, LogSw

-5.23

Polar Surface Area

62.911

Acid Dissociation Constant (pKa)

14.56

Base Dissociation Constant (pKb)

3.81

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.40

F067-1439 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F067-1439 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F067-1439?
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What is the minimum amount of F067-1439 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F067-1439
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F067-1439
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F067-1439 available by request