F072-0136 Screening compound: 3-(4-fluorophenyl)-N-[(4-methylphenyl)methyl]-2-(morpholin-4-yl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide

F072-0136 Screening compound: 3-(4-fluorophenyl)-N-[(4-methylphenyl)methyl]-2-(morpholin-4-yl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide
F072-0136 Screening compound: 3-(4-fluorophenyl)-N-[(4-methylphenyl)methyl]-2-(morpholin-4-yl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F072-0136
3-(4-fluorophenyl)-N-[(4-methylphenyl)methyl]-2-(morpholin-4-yl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F072-0136

Molecular Formula

C27H25FN4O3 (C27 H25 FN4 O3)

Compound Name

3-(4-fluorophenyl)-N-[(4-methylphenyl)methyl]-2-(morpholin-4-yl)-4-oxo-3,4-dihydroquinazoline-7-carboxamide

IUPAC name

3-(4-fluorophenyl)-N-[(4-methylphenyl)methyl]-2-(morpholin-4-yl)-4-oxo-34-dihydroquinazoline-7-carboxamide

SMILES

Cc1ccc(CNC(c(cc2)cc(N=C(N3CCOCC3)N3c(cc4)ccc4F)c2C3=O)=O)cc1

InChI

InChI=1S/C27H25FN4O3/c1-18-2-4-19(5-3-18)17-29-25(33)20-6-11-23-24(16-20)30-27(31-12-14-35-15-13-31)32(26(23)34)22-9-7-21(28)8-10-22/h2-11,16H,12-15,17H2,1H3,(H,29,33)

InChI Key

ACQGGWNSEMIAEZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27099079

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.092

Distribution Coefficient, logD

3.092

Water Solubility, LogSw

-3.34

Polar Surface Area

60.533

Acid Dissociation Constant (pKa)

11.43

Base Dissociation Constant (pKb)

4.08

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

F072-0136 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with F072-0136 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F072-0136?
Check Price and Availability of F072-0136, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F072-0136 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F072-0136
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F072-0136
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F072-0136 available by request