F080-0486 Screening compound: 6-fluoro-N-(3-methylphenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine

F080-0486 Screening compound: 6-fluoro-N-(3-methylphenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine
F080-0486 Screening compound: 6-fluoro-N-(3-methylphenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound F080-0486
6-fluoro-N-(3-methylphenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F080-0486

Molecular Formula

C21H20FN3O2 (C21 H20 FN3 O2)

Compound Name

6-fluoro-N-(3-methylphenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine

IUPAC name

6-fluoro-N-(3-methylphenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine

SMILES

Cc1cccc(Nc2c(cc(cc3)F)c3ncc2C(N2CCOCC2)=O)c1

InChI

InChI=1S/C21H20FN3O2/c1-14-3-2-4-16(11-14)24-20-17-12-15(22)5-6-19(17)23-13-18(20)21(26)25-7-9-27-10-8-25/h2-6,11-13H,7-10H2,1H3,(H,23,24)

InChI Key

UZNDRTMPSFVEKQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27099759

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.216

Distribution Coefficient, logD

3.213

Water Solubility, LogSw

-3.20

Polar Surface Area

41.164

Acid Dissociation Constant (pKa)

17.06

Base Dissociation Constant (pKb)

5.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

F080-0486 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

PI3K-Targeted Library (17255 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with F080-0486 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F080-0486?
Check Price and Availability of F080-0486, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F080-0486 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F080-0486
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F080-0486
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F080-0486 available by request