F080-0488 Screening compound: N-(2-chlorophenyl)-6-fluoro-3-(morpholine-4-carbonyl)quinolin-4-amine

F080-0488 Screening compound: N-(2-chlorophenyl)-6-fluoro-3-(morpholine-4-carbonyl)quinolin-4-amine
F080-0488 Screening compound: N-(2-chlorophenyl)-6-fluoro-3-(morpholine-4-carbonyl)quinolin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound F080-0488
N-(2-chlorophenyl)-6-fluoro-3-(morpholine-4-carbonyl)quinolin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F080-0488

Molecular Formula

C20H17ClFN3O2 (C20 H17 ClFN3 O2)

Compound Name

N-(2-chlorophenyl)-6-fluoro-3-(morpholine-4-carbonyl)quinolin-4-amine

IUPAC name

N-(2-chlorophenyl)-6-fluoro-3-(morpholine-4-carbonyl)quinolin-4-amine

SMILES

O=C(c(cnc(c1c2)ccc2F)c1Nc(cccc1)c1Cl)N1CCOCC1

InChI

InChI=1S/C20H17ClFN3O2/c21-16-3-1-2-4-18(16)24-19-14-11-13(22)5-6-17(14)23-12-15(19)20(26)25-7-9-27-10-8-25/h1-6,11-12H,7-10H2,(H,23,24)

InChI Key

VKJBVENDAAYQTO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27099761

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

385.83

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.344

Distribution Coefficient, logD

3.342

Water Solubility, LogSw

-3.59

Polar Surface Area

40.467

Acid Dissociation Constant (pKa)

14.99

Base Dissociation Constant (pKb)

5.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

F080-0488 in Drug Discovery

Included in Screening Libraries

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with F080-0488 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F080-0488?
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What is the minimum amount of F080-0488 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F080-0488
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F080-0488
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F080-0488 available by request