F080-0491 Screening compound: 6-fluoro-N-(2-fluorophenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine

F080-0491 Screening compound: 6-fluoro-N-(2-fluorophenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine
F080-0491 Screening compound: 6-fluoro-N-(2-fluorophenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound F080-0491
6-fluoro-N-(2-fluorophenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F080-0491

Molecular Formula

C20H17F2N3O2 (C20 H17 F2 N3 O2)

Compound Name

6-fluoro-N-(2-fluorophenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine

IUPAC name

6-fluoro-N-(2-fluorophenyl)-3-(morpholine-4-carbonyl)quinolin-4-amine

SMILES

O=C(c(cnc(c1c2)ccc2F)c1Nc(cccc1)c1F)N1CCOCC1

InChI

InChI=1S/C20H17F2N3O2/c21-13-5-6-17-14(11-13)19(24-18-4-2-1-3-16(18)22)15(12-23-17)20(26)25-7-9-27-10-8-25/h1-6,11-12H,7-10H2,(H,23,24)

InChI Key

SJRRUBZLPAMQEG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27099763

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

369.37

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.073

Distribution Coefficient, logD

3.071

Water Solubility, LogSw

-3.21

Polar Surface Area

40.467

Acid Dissociation Constant (pKa)

14.99

Base Dissociation Constant (pKb)

5.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

20.00

F080-0491 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with F080-0491 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F080-0491?
Check Price and Availability of F080-0491, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F080-0491 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F080-0491
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F080-0491
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F080-0491 available by request