F091-0659 Screening compound: N2-(3-chloro-4-fluorophenyl)-5-(4-methylbenzoyl)-1,3-thiazole-2,4-diamine

F091-0659 Screening compound: N2-(3-chloro-4-fluorophenyl)-5-(4-methylbenzoyl)-1,3-thiazole-2,4-diamine
F091-0659 Screening compound: N2-(3-chloro-4-fluorophenyl)-5-(4-methylbenzoyl)-1,3-thiazole-2,4-diamine alternative view

Chemical Structure Depiction of ChemDiv screening compound F091-0659
N2-(3-chloro-4-fluorophenyl)-5-(4-methylbenzoyl)-1,3-thiazole-2,4-diamine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F091-0659

Molecular Formula

C17H13ClFN3OS (C17 H13 ClFN3 OS)

Compound Name

N2-(3-chloro-4-fluorophenyl)-5-(4-methylbenzoyl)-1,3-thiazole-2,4-diamine

IUPAC name

N2-(3-chloro-4-fluorophenyl)-5-(4-methylbenzoyl)-13-thiazole-24-diamine

SMILES

Cc(cc1)ccc1C(c1c(N)nc(Nc(cc2)cc(Cl)c2F)s1)=O

InChI

InChI=1S/C17H13ClFN3OS/c1-9-2-4-10(5-3-9)14(23)15-16(20)22-17(24-15)21-11-6-7-13(19)12(18)8-11/h2-8H,20H2,1H3,(H,21,22)

InChI Key

HODVWPVERAZWJD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14940799

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

361.83

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.334

Distribution Coefficient, logD

5.334

Water Solubility, LogSw

-5.93

Polar Surface Area

53.361

Acid Dissociation Constant (pKa)

15.16

Base Dissociation Constant (pKb)

2.49

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

5.90

F091-0659 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F091-0659 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F091-0659?
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What is the minimum amount of F091-0659 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F091-0659
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F091-0659
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F091-0659 available by request