F108-1151 Screening compound: N-[1,3-bis(4-fluorophenyl)propan-2-yl]-3-methoxybenzamide

F108-1151 Screening compound: N-[1,3-bis(4-fluorophenyl)propan-2-yl]-3-methoxybenzamide
F108-1151 Screening compound: N-[1,3-bis(4-fluorophenyl)propan-2-yl]-3-methoxybenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F108-1151
N-[1,3-bis(4-fluorophenyl)propan-2-yl]-3-methoxybenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F108-1151

Molecular Formula

C23H21F2NO2 (C23 H21 F2 NO2)

Compound Name

N-[1,3-bis(4-fluorophenyl)propan-2-yl]-3-methoxybenzamide

IUPAC name

N-[13-bis(4-fluorophenyl)propan-2-yl]-3-methoxybenzamide

SMILES

COc1cccc(C(NC(Cc(cc2)ccc2F)Cc(cc2)ccc2F)=O)c1

InChI

InChI=1S/C23H21F2NO2/c1-28-22-4-2-3-18(15-22)23(27)26-21(13-16-5-9-19(24)10-6-16)14-17-7-11-20(25)12-8-17/h2-12,15,21H,13-14H2,1H3,(H,26,27)

InChI Key

MKMIDCSZIWMAIP-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14941419

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.42

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

5.203

Distribution Coefficient, logD

5.203

Water Solubility, LogSw

-5.14

Polar Surface Area

31.833

Acid Dissociation Constant (pKa)

13.16

Base Dissociation Constant (pKb)

-2.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

17.40

F108-1151 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Glucocorticoid receptors Library (4806 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
  • Endocrine
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Nuclear receptors
  • Proteases
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F108-1151 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F108-1151?
Check Price and Availability of F108-1151, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F108-1151 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F108-1151
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F108-1151
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F108-1151 available by request