F111-0622 Screening compound: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{2-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}acetamide

F111-0622 Screening compound: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{2-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}acetamide
F111-0622 Screening compound: 2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{2-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F111-0622
2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{2-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F111-0622

Molecular Formula

C24H18FN5O3 (C24 H18 FN5 O3)

Compound Name

2-(1,3-dioxo-2,3-dihydro-1H-isoindol-2-yl)-N-{2-[2-(4-fluorophenyl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}acetamide

IUPAC name

2-(13-dioxo-23-dihydro-1H-isoindol-2-yl)-N-{2-[2-(4-fluorophenyl)-3H-imidazo[45-b]pyridin-3-yl]ethyl}acetamide

SMILES

O=C(CN(C(c1c2cccc1)=O)C2=O)NCCn1c(-c(cc2)ccc2F)nc2c1nccc2

InChI

InChI=1S/C24H18FN5O3/c25-16-9-7-15(8-10-16)21-28-19-6-3-11-27-22(19)29(21)13-12-26-20(31)14-30-23(32)17-4-1-2-5-18(17)24(30)33/h1-11H,12-14H2,(H,26,31)

InChI Key

UDUAWZSEKBRGID-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14941488

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

443.44

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.712

Distribution Coefficient, logD

2.712

Water Solubility, LogSw

-3.27

Polar Surface Area

73.618

Acid Dissociation Constant (pKa)

14.92

Base Dissociation Constant (pKb)

3.69

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

F111-0622 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

MCL1 Targeted Library (12200 compounds)

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F111-0622 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F111-0622?
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What is the minimum amount of F111-0622 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F111-0622
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F111-0622
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F111-0622 available by request