F112-0583 Screening compound: N-{2-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}-2,1,3-benzothiadiazole-4-sulfonamide

F112-0583 Screening compound: N-{2-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}-2,1,3-benzothiadiazole-4-sulfonamide
F112-0583 Screening compound: N-{2-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}-2,1,3-benzothiadiazole-4-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F112-0583
N-{2-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}-2,1,3-benzothiadiazole-4-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F112-0583

Molecular Formula

C19H15N7O2S2 (C19 H15 N7 O2 S2)

Compound Name

N-{2-[2-(pyridin-4-yl)-3H-imidazo[4,5-b]pyridin-3-yl]ethyl}-2,1,3-benzothiadiazole-4-sulfonamide

IUPAC name

N-{2-[2-(pyridin-4-yl)-3H-imidazo[45-b]pyridin-3-yl]ethyl}-213-benzothiadiazole-4-sulfonamide

SMILES

O=S(c1cccc2nsnc12)(NCCn1c(-c2ccncc2)nc2cccnc12)=O

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.51

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.621

Distribution Coefficient, logD

2.619

Water Solubility, LogSw

-2.73

Polar Surface Area

92.033

Acid Dissociation Constant (pKa)

9.83

Base Dissociation Constant (pKb)

4.78

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

F112-0583 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F112-0583 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F112-0583?
Check Price and Availability of F112-0583, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F112-0583 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F112-0583
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F112-0583
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F112-0583 available by request