F114-0646 Screening compound: N-(2-fluorophenyl)-4-[2-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-3-yl]piperidine-1-carboxamide

F114-0646 Screening compound: N-(2-fluorophenyl)-4-[2-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-3-yl]piperidine-1-carboxamide
F114-0646 Screening compound: N-(2-fluorophenyl)-4-[2-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-3-yl]piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F114-0646
N-(2-fluorophenyl)-4-[2-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-3-yl]piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F114-0646

Molecular Formula

C22H26FN5O (C22 H26 FN5 O)

Compound Name

N-(2-fluorophenyl)-4-[2-(2-methylpropyl)-3H-imidazo[4,5-b]pyridin-3-yl]piperidine-1-carboxamide

IUPAC name

N-(2-fluorophenyl)-4-[2-(2-methylpropyl)-3H-imidazo[45-b]pyridin-3-yl]piperidine-1-carboxamide

SMILES

CC(C)Cc1nc2cccnc2n1C(CC1)CCN1C(Nc(cccc1)c1F)=O

InChI

InChI=1S/C22H26FN5O/c1-15(2)14-20-25-19-8-5-11-24-21(19)28(20)16-9-12-27(13-10-16)22(29)26-18-7-4-3-6-17(18)23/h3-8,11,15-16H,9-10,12-14H2,1-2H3,(H,26,29)

InChI Key

HDULKQFHIIYTTA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14941841

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

395.48

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.227

Distribution Coefficient, logD

4.227

Water Solubility, LogSw

-4.03

Polar Surface Area

46.205

Acid Dissociation Constant (pKa)

12.14

Base Dissociation Constant (pKb)

3.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.90

F114-0646 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F114-0646 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F114-0646?
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What is the minimum amount of F114-0646 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F114-0646
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F114-0646
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F114-0646 available by request