F127-0237 Screening compound: 8-chloro-2-[(3,5-dimethylphenyl)amino]-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one

F127-0237 Screening compound: 8-chloro-2-[(3,5-dimethylphenyl)amino]-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one
F127-0237 Screening compound: 8-chloro-2-[(3,5-dimethylphenyl)amino]-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F127-0237
8-chloro-2-[(3,5-dimethylphenyl)amino]-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F127-0237

Molecular Formula

C17H13ClN4OS (C17 H13 ClN4 OS)

Compound Name

8-chloro-2-[(3,5-dimethylphenyl)amino]-5H-[1,3,4]thiadiazolo[2,3-b]quinazolin-5-one

IUPAC name

8-chloro-2-[(35-dimethylphenyl)amino]-5H-[134]thiadiazolo[23-b]quinazolin-5-one

SMILES

Cc1cc(NC(SC2=Nc3c4ccc(Cl)c3)=NN2C4=O)cc(C)c1

InChI

InChI=1S/C17H13ClN4OS/c1-9-5-10(2)7-12(6-9)19-16-21-22-15(23)13-4-3-11(18)8-14(13)20-17(22)24-16/h3-8H,1-2H3,(H,19,21)

InChI Key

KZGOTGYTRCBKOF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27103361

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.84

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.377

Distribution Coefficient, logD

4.352

Water Solubility, LogSw

-4.55

Polar Surface Area

46.867

Acid Dissociation Constant (pKa)

9.84

Base Dissociation Constant (pKb)

6.15

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

11.80

F127-0237 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal

References: we are preparing a list of scientific research reports with F127-0237 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F127-0237?
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What is the minimum amount of F127-0237 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F127-0237
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F127-0237
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F127-0237 available by request