F142-0218 Screening compound: 5-(1-{[(3-chlorophenyl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-(propan-2-yl)pentanamide

F142-0218 Screening compound: 5-(1-{[(3-chlorophenyl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-(propan-2-yl)pentanamide
F142-0218 Screening compound: 5-(1-{[(3-chlorophenyl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-(propan-2-yl)pentanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F142-0218
5-(1-{[(3-chlorophenyl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-(propan-2-yl)pentanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F142-0218

Molecular Formula

C24H27ClN4O4 (C24 H27 ClN4 O4)

Compound Name

5-(1-{[(3-chlorophenyl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-(propan-2-yl)pentanamide

IUPAC name

5-(1-{[(3-chlorophenyl)carbamoyl]methyl}-24-dioxo-1234-tetrahydroquinazolin-3-yl)-N-(propan-2-yl)pentanamide

SMILES

CC(C)NC(CCCCN(C(c(cccc1)c1N1CC(Nc2cccc(Cl)c2)=O)=O)C1=O)=O

InChI

InChI=1S/C24H27ClN4O4/c1-16(2)26-21(30)12-5-6-13-28-23(32)19-10-3-4-11-20(19)29(24(28)33)15-22(31)27-18-9-7-8-17(25)14-18/h3-4,7-11,14,16H,5-6,12-13,15H2,1-2H3,(H,26,30)(H,27,31)

InChI Key

OBKSXOAKXHFKFG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11993995

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.96

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.140

Distribution Coefficient, logD

3.140

Water Solubility, LogSw

-3.68

Polar Surface Area

78.112

Acid Dissociation Constant (pKa)

10.97

Base Dissociation Constant (pKb)

1.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

F142-0218 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Targeted Diversity Library (40567 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with F142-0218 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F142-0218?
Check Price and Availability of F142-0218, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F142-0218 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F142-0218
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F142-0218
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F142-0218 available by request