F142-0627 Screening compound: 5-(1-{[(2H-1,3-benzodioxol-5-yl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-cyclopentylpentanamide

F142-0627 Screening compound: 5-(1-{[(2H-1,3-benzodioxol-5-yl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-cyclopentylpentanamide
F142-0627 Screening compound: 5-(1-{[(2H-1,3-benzodioxol-5-yl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-cyclopentylpentanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F142-0627
5-(1-{[(2H-1,3-benzodioxol-5-yl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-cyclopentylpentanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F142-0627

Molecular Formula

C27H30N4O6 (C27 H30 N4 O6)

Compound Name

5-(1-{[(2H-1,3-benzodioxol-5-yl)carbamoyl]methyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl)-N-cyclopentylpentanamide

IUPAC name

5-(1-{[(2H-13-benzodioxol-5-yl)carbamoyl]methyl}-24-dioxo-1234-tetrahydroquinazolin-3-yl)-N-cyclopentylpentanamide

SMILES

O=C(CCCCN(C(c(cccc1)c1N1CC(Nc(cc2)cc3c2OCO3)=O)=O)C1=O)NC1CCCC1

InChI

InChI=1S/C27H30N4O6/c32-24(28-18-7-1-2-8-18)11-5-6-14-30-26(34)20-9-3-4-10-21(20)31(27(30)35)16-25(33)29-19-12-13-22-23(15-19)37-17-36-22/h3-4,9-10,12-13,15,18H,1-2,5-8,11,14,16-17H2,(H,28,32)(H,29,33)

InChI Key

GMKKPMFXKGFRNB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27104143

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

506.56

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.901

Distribution Coefficient, logD

2.901

Water Solubility, LogSw

-3.62

Polar Surface Area

96.073

Acid Dissociation Constant (pKa)

11.54

Base Dissociation Constant (pKb)

1.35

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.70

F142-0627 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with F142-0627 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F142-0627?
Check Price and Availability of F142-0627, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F142-0627 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F142-0627
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F142-0627
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F142-0627 available by request