F143-0285 Screening compound: 3-(4-chlorophenyl)-5-{[(3-chlorophenyl)methyl]sulfanyl}-6-methyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

F143-0285 Screening compound: 3-(4-chlorophenyl)-5-{[(3-chlorophenyl)methyl]sulfanyl}-6-methyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
F143-0285 Screening compound: 3-(4-chlorophenyl)-5-{[(3-chlorophenyl)methyl]sulfanyl}-6-methyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F143-0285
3-(4-chlorophenyl)-5-{[(3-chlorophenyl)methyl]sulfanyl}-6-methyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F143-0285

Molecular Formula

C19H13Cl2N3OS3 (C19 H13 Cl2 N3 OS3)

Compound Name

3-(4-chlorophenyl)-5-{[(3-chlorophenyl)methyl]sulfanyl}-6-methyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

3-(4-chlorophenyl)-5-{[(3-chlorophenyl)methyl]sulfanyl}-6-methyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

CN(C1=O)C(SCc2cccc(Cl)c2)=NC(N2c(cc3)ccc3Cl)=C1SC2=S

InChI

InChI=1S/C19H13Cl2N3OS3/c1-23-17(25)15-16(22-18(23)27-10-11-3-2-4-13(21)9-11)24(19(26)28-15)14-7-5-12(20)6-8-14/h2-9H,10H2,1H3

InChI Key

DWSHFHZHGMROFA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943036

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

5.383

Distribution Coefficient, logD

5.383

Water Solubility, LogSw

-5.84

Polar Surface Area

27.603

Acid Dissociation Constant (pKa)

33.87

Base Dissociation Constant (pKb)

-3.55

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

10.50

F143-0285 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with F143-0285 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F143-0285?
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What is the minimum amount of F143-0285 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F143-0285
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F143-0285
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F143-0285 available by request