F143-0382 Screening compound: 5-{[(2,5-dimethylphenyl)methyl]sulfanyl}-3-(4-ethoxyphenyl)-6-methyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

F143-0382 Screening compound: 5-{[(2,5-dimethylphenyl)methyl]sulfanyl}-3-(4-ethoxyphenyl)-6-methyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one
F143-0382 Screening compound: 5-{[(2,5-dimethylphenyl)methyl]sulfanyl}-3-(4-ethoxyphenyl)-6-methyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F143-0382
5-{[(2,5-dimethylphenyl)methyl]sulfanyl}-3-(4-ethoxyphenyl)-6-methyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F143-0382

Molecular Formula

C23H23N3O2S3 (C23 H23 N3 O2 S3)

Compound Name

5-{[(2,5-dimethylphenyl)methyl]sulfanyl}-3-(4-ethoxyphenyl)-6-methyl-2-sulfanylidene-2H,3H,6H,7H-[1,3]thiazolo[4,5-d]pyrimidin-7-one

IUPAC name

5-{[(25-dimethylphenyl)methyl]sulfanyl}-3-(4-ethoxyphenyl)-6-methyl-2-sulfanylidene-2H3H6H7H-[13]thiazolo[45-d]pyrimidin-7-one

SMILES

CCOc(cc1)ccc1N(C(N=C(N(C)C1=O)SCc2c(C)ccc(C)c2)=C1S1)C1=S

InChI

InChI=1S/C23H23N3O2S3/c1-5-28-18-10-8-17(9-11-18)26-20-19(31-23(26)29)21(27)25(4)22(24-20)30-13-16-12-14(2)6-7-15(16)3/h6-12H,5,13H2,1-4H3

InChI Key

VXIXMHAEAVRVQW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943068

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

469.65

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.729

Distribution Coefficient, logD

5.729

Water Solubility, LogSw

-5.24

Polar Surface Area

34.727

Acid Dissociation Constant (pKa)

28.43

Base Dissociation Constant (pKb)

2.66

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.10

F143-0382 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system

References: we are preparing a list of scientific research reports with F143-0382 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F143-0382?
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What is the minimum amount of F143-0382 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F143-0382
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F143-0382
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F143-0382 available by request