F144-0113 Screening compound: 2-(4-{1-[(3-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}phenyl)-N-methylacetamide

F144-0113 Screening compound: 2-(4-{1-[(3-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}phenyl)-N-methylacetamide
F144-0113 Screening compound: 2-(4-{1-[(3-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}phenyl)-N-methylacetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F144-0113
2-(4-{1-[(3-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}phenyl)-N-methylacetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F144-0113

Molecular Formula

C24H20ClN3O3 (C24 H20 ClN3 O3)

Compound Name

2-(4-{1-[(3-chlorophenyl)methyl]-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-3-yl}phenyl)-N-methylacetamide

IUPAC name

2-(4-{1-[(3-chlorophenyl)methyl]-24-dioxo-1234-tetrahydroquinazolin-3-yl}phenyl)-N-methylacetamide

SMILES

CNC(Cc(cc1)ccc1N(C(c(cccc1)c1N1Cc2cccc(Cl)c2)=O)C1=O)=O

InChI

InChI=1S/C24H20ClN3O3/c1-26-22(29)14-16-9-11-19(12-10-16)28-23(30)20-7-2-3-8-21(20)27(24(28)31)15-17-5-4-6-18(25)13-17/h2-13H,14-15H2,1H3,(H,26,29)

InChI Key

SLNGFKREKGAUID-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27104308

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

433.89

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.853

Distribution Coefficient, logD

2.853

Water Solubility, LogSw

-3.73

Polar Surface Area

55.277

Acid Dissociation Constant (pKa)

14.72

Base Dissociation Constant (pKb)

-0.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

12.50

F144-0113 in Drug Discovery

Included in Screening Libraries

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with F144-0113 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F144-0113?
Check Price and Availability of F144-0113, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F144-0113 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F144-0113
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F144-0113
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F144-0113 available by request