F144-0168 Screening compound: N-[(4-methoxyphenyl)methyl]-2-(3-{4-[(methylcarbamoyl)methyl]phenyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl)acetamide

F144-0168 Screening compound: N-[(4-methoxyphenyl)methyl]-2-(3-{4-[(methylcarbamoyl)methyl]phenyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl)acetamide
F144-0168 Screening compound: N-[(4-methoxyphenyl)methyl]-2-(3-{4-[(methylcarbamoyl)methyl]phenyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F144-0168
N-[(4-methoxyphenyl)methyl]-2-(3-{4-[(methylcarbamoyl)methyl]phenyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F144-0168

Molecular Formula

C27H26N4O5 (C27 H26 N4 O5)

Compound Name

N-[(4-methoxyphenyl)methyl]-2-(3-{4-[(methylcarbamoyl)methyl]phenyl}-2,4-dioxo-1,2,3,4-tetrahydroquinazolin-1-yl)acetamide

IUPAC name

N-[(4-methoxyphenyl)methyl]-2-(3-{4-[(methylcarbamoyl)methyl]phenyl}-24-dioxo-1234-tetrahydroquinazolin-1-yl)acetamide

SMILES

CNC(Cc(cc1)ccc1N(C(c(cccc1)c1N1CC(NCc(cc2)ccc2OC)=O)=O)C1=O)=O

InChI

InChI=1S/C27H26N4O5/c1-28-24(32)15-18-7-11-20(12-8-18)31-26(34)22-5-3-4-6-23(22)30(27(31)35)17-25(33)29-16-19-9-13-21(36-2)14-10-19/h3-14H,15-17H2,1-2H3,(H,28,32)(H,29,33)

InChI Key

YKIKGKNLLJVEBN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11993711

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

486.53

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.164

Distribution Coefficient, logD

1.164

Water Solubility, LogSw

-2.43

Polar Surface Area

87.293

Acid Dissociation Constant (pKa)

14.43

Base Dissociation Constant (pKb)

-0.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

18.50

F144-0168 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics

References: we are preparing a list of scientific research reports with F144-0168 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F144-0168?
Check Price and Availability of F144-0168, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F144-0168 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F144-0168
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F144-0168
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F144-0168 available by request