F146-1127 Screening compound: 3-(4-methylphenyl)-4-[4-(4-nitrophenyl)piperazine-1-carbonyl]cinnoline

F146-1127 Screening compound: 3-(4-methylphenyl)-4-[4-(4-nitrophenyl)piperazine-1-carbonyl]cinnoline
F146-1127 Screening compound: 3-(4-methylphenyl)-4-[4-(4-nitrophenyl)piperazine-1-carbonyl]cinnoline alternative view

Chemical Structure Depiction of ChemDiv screening compound F146-1127
3-(4-methylphenyl)-4-[4-(4-nitrophenyl)piperazine-1-carbonyl]cinnoline

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F146-1127

Molecular Formula

C26H23N5O3 (C26 H23 N5 O3)

Compound Name

3-(4-methylphenyl)-4-[4-(4-nitrophenyl)piperazine-1-carbonyl]cinnoline

IUPAC name

3-(4-methylphenyl)-4-[4-(4-nitrophenyl)piperazine-1-carbonyl]cinnoline

SMILES

Cc(cc1)ccc1-c1c(C(N(CC2)CCN2c(cc2)ccc2[N+]([O-])=O)=O)c2ccccc2nn1

InChI

InChI=1S/C26H23N5O3/c1-18-6-8-19(9-7-18)25-24(22-4-2-3-5-23(22)27-28-25)26(32)30-16-14-29(15-17-30)20-10-12-21(13-11-20)31(33)34/h2-13H,14-17H2,1H3

InChI Key

XANIWMAEBPXGCB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943156

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.5

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.364

Distribution Coefficient, logD

4.364

Water Solubility, LogSw

-4.46

Polar Surface Area

75.485

Acid Dissociation Constant (pKa)

27.76

Base Dissociation Constant (pKb)

4.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

F146-1127 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with F146-1127 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F146-1127?
Check Price and Availability of F146-1127, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F146-1127 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F146-1127
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F146-1127
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F146-1127 available by request