F146-1233 Screening compound: N-[3-(4-benzylpiperazin-1-yl)propyl]-3-(4-methylphenyl)cinnoline-4-carboxamide

F146-1233 Screening compound: N-[3-(4-benzylpiperazin-1-yl)propyl]-3-(4-methylphenyl)cinnoline-4-carboxamide
F146-1233 Screening compound: N-[3-(4-benzylpiperazin-1-yl)propyl]-3-(4-methylphenyl)cinnoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F146-1233
N-[3-(4-benzylpiperazin-1-yl)propyl]-3-(4-methylphenyl)cinnoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F146-1233

Molecular Formula

C30H33N5O (C30 H33 N5 O)

Compound Name

N-[3-(4-benzylpiperazin-1-yl)propyl]-3-(4-methylphenyl)cinnoline-4-carboxamide

IUPAC name

N-[3-(4-benzylpiperazin-1-yl)propyl]-3-(4-methylphenyl)cinnoline-4-carboxamide

SMILES

Cc(cc1)ccc1-c1c(C(NCCCN2CCN(Cc3ccccc3)CC2)=O)c2ccccc2nn1

InChI

InChI=1S/C30H33N5O/c1-23-12-14-25(15-13-23)29-28(26-10-5-6-11-27(26)32-33-29)30(36)31-16-7-17-34-18-20-35(21-19-34)22-24-8-3-2-4-9-24/h2-6,8-15H,7,16-22H2,1H3,(H,31,36)

InChI Key

FJWDNKREUDBITC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943211

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

479.63

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.679

Distribution Coefficient, logD

2.908

Water Solubility, LogSw

-4.09

Polar Surface Area

53.973

Acid Dissociation Constant (pKa)

15.93

Base Dissociation Constant (pKb)

8.09

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

F146-1233 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F146-1233 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F146-1233?
Check Price and Availability of F146-1233, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F146-1233 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F146-1233
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F146-1233
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F146-1233 available by request