F146-1779 Screening compound: N-(1-benzylpiperidin-4-yl)-3-phenylcinnoline-4-carboxamide

F146-1779 Screening compound: N-(1-benzylpiperidin-4-yl)-3-phenylcinnoline-4-carboxamide
F146-1779 Screening compound: N-(1-benzylpiperidin-4-yl)-3-phenylcinnoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F146-1779
N-(1-benzylpiperidin-4-yl)-3-phenylcinnoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F146-1779

Molecular Formula

C27H26N4O (C27 H26 N4 O)

Compound Name

N-(1-benzylpiperidin-4-yl)-3-phenylcinnoline-4-carboxamide

IUPAC name

N-(1-benzylpiperidin-4-yl)-3-phenylcinnoline-4-carboxamide

SMILES

O=C(c1c(-c2ccccc2)nnc2ccccc12)NC1CCN(Cc2ccccc2)CC1

InChI

InChI=1S/C27H26N4O/c32-27(28-22-15-17-31(18-16-22)19-20-9-3-1-4-10-20)25-23-13-7-8-14-24(23)29-30-26(25)21-11-5-2-6-12-21/h1-14,22H,15-19H2,(H,28,32)

InChI Key

FURXHAIJIRVEGZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943301

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

422.53

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.722

Distribution Coefficient, logD

2.277

Water Solubility, LogSw

-4.40

Polar Surface Area

49.874

Acid Dissociation Constant (pKa)

16.56

Base Dissociation Constant (pKb)

8.83

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

F146-1779 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Anti-HIV1 Library (19540 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Antiviral
  • Infections
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with F146-1779 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F146-1779?
Check Price and Availability of F146-1779, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F146-1779 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F146-1779
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F146-1779
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F146-1779 available by request