F146-1808 Screening compound: N-(6-ethoxy-1,3-benzothiazol-2-yl)-3-phenylcinnoline-4-carboxamide

F146-1808 Screening compound: N-(6-ethoxy-1,3-benzothiazol-2-yl)-3-phenylcinnoline-4-carboxamide
F146-1808 Screening compound: N-(6-ethoxy-1,3-benzothiazol-2-yl)-3-phenylcinnoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F146-1808
N-(6-ethoxy-1,3-benzothiazol-2-yl)-3-phenylcinnoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F146-1808

Molecular Formula

C24H18N4O2S (C24 H18 N4 O2 S)

Compound Name

N-(6-ethoxy-1,3-benzothiazol-2-yl)-3-phenylcinnoline-4-carboxamide

IUPAC name

N-(6-ethoxy-13-benzothiazol-2-yl)-3-phenylcinnoline-4-carboxamide

SMILES

CCOc(cc1)cc2c1nc(NC(c1c(-c3ccccc3)nnc3ccccc13)=O)s2

InChI

InChI=1S/C24H18N4O2S/c1-2-30-16-12-13-19-20(14-16)31-24(25-19)26-23(29)21-17-10-6-7-11-18(17)27-28-22(21)15-8-4-3-5-9-15/h3-14H,2H2,1H3,(H,25,26,29)

InChI Key

QHICDSIEAXWIKQ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943315

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.5

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.318

Distribution Coefficient, logD

5.318

Water Solubility, LogSw

-5.67

Polar Surface Area

62.171

Acid Dissociation Constant (pKa)

11.85

Base Dissociation Constant (pKb)

2.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

8.30

F146-1808 in Drug Discovery

Included in Screening Libraries

Allosteric Kinases Inhibitors Library (23117 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Akt-Targeted Library (14764 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Female
  • Congenital
  • Skin
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Targets:
  • Kinases
  • Kinases
  • Kinases
  • Phosphatases

References: we are preparing a list of scientific research reports with F146-1808 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F146-1808?
Check Price and Availability of F146-1808, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F146-1808 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F146-1808
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F146-1808
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F146-1808 available by request