F146-1923 Screening compound: 3-phenyl-N-{4-[(pyrrolidin-1-yl)methyl]phenyl}cinnoline-4-carboxamide

F146-1923 Screening compound: 3-phenyl-N-{4-[(pyrrolidin-1-yl)methyl]phenyl}cinnoline-4-carboxamide
F146-1923 Screening compound: 3-phenyl-N-{4-[(pyrrolidin-1-yl)methyl]phenyl}cinnoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F146-1923
3-phenyl-N-{4-[(pyrrolidin-1-yl)methyl]phenyl}cinnoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F146-1923

Molecular Formula

C26H24N4O (C26 H24 N4 O)

Compound Name

3-phenyl-N-{4-[(pyrrolidin-1-yl)methyl]phenyl}cinnoline-4-carboxamide

IUPAC name

3-phenyl-N-{4-[(pyrrolidin-1-yl)methyl]phenyl}cinnoline-4-carboxamide

SMILES

O=C(c1c(-c2ccccc2)nnc2ccccc12)Nc1ccc(CN2CCCC2)cc1

InChI

InChI=1S/C26H24N4O/c31-26(27-21-14-12-19(13-15-21)18-30-16-6-7-17-30)24-22-10-4-5-11-23(22)28-29-25(24)20-8-2-1-3-9-20/h1-5,8-15H,6-7,16-18H2,(H,27,31)

InChI Key

ZHPPRKHCNXPKLG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943362

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

408.5

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.073

Distribution Coefficient, logD

2.061

Water Solubility, LogSw

-4.37

Polar Surface Area

49.385

Acid Dissociation Constant (pKa)

12.36

Base Dissociation Constant (pKb)

9.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

19.20

F146-1923 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

Anti-infective Library (19449 compounds)

Antifungal Library (16415 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Infections
  • Immune system
  • animal
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Agro:
  • Agro
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with F146-1923 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F146-1923?
Check Price and Availability of F146-1923, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F146-1923 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F146-1923
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F146-1923
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F146-1923 available by request