F147-0878 Screening compound: 2-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}-N-(2,3,5,6-tetrafluorophenyl)acetamide

F147-0878 Screening compound: 2-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}-N-(2,3,5,6-tetrafluorophenyl)acetamide
F147-0878 Screening compound: 2-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}-N-(2,3,5,6-tetrafluorophenyl)acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F147-0878
2-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}-N-(2,3,5,6-tetrafluorophenyl)acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F147-0878

Molecular Formula

C14H12F4N4O3S (C14 H12 F4 N4 O3 S)

Compound Name

2-{[4-(morpholin-4-yl)-1,2,5-thiadiazol-3-yl]oxy}-N-(2,3,5,6-tetrafluorophenyl)acetamide

IUPAC name

2-{[4-(morpholin-4-yl)-125-thiadiazol-3-yl]oxy}-N-(2356-tetrafluorophenyl)acetamide

SMILES

O=C(COc1nsnc1N1CCOCC1)Nc(c(F)c(cc1F)F)c1F

InChI

InChI=1S/C14H12F4N4O3S/c15-7-5-8(16)11(18)12(10(7)17)19-9(23)6-25-14-13(20-26-21-14)22-1-3-24-4-2-22/h5H,1-4,6H2,(H,19,23)

InChI Key

KLKMWCKMELQZGO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943436

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.33

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

2.916

Distribution Coefficient, logD

0.677

Water Solubility, LogSw

-3.29

Polar Surface Area

61.752

Acid Dissociation Constant (pKa)

5.16

Base Dissociation Constant (pKb)

-0.29

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

35.70

F147-0878 in Drug Discovery

Included in Screening Libraries

CNS MPO Library (28609 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F147-0878 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F147-0878?
Check Price and Availability of F147-0878, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F147-0878 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F147-0878
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F147-0878
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F147-0878 available by request