F148-0506 Screening compound: 7-benzyl-N~3~-(2,3-dimethylphenyl)-4-methyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

F148-0506 Screening compound: 7-benzyl-N~3~-(2,3-dimethylphenyl)-4-methyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide
F148-0506 Screening compound: 7-benzyl-N~3~-(2,3-dimethylphenyl)-4-methyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F148-0506
7-benzyl-N~3~-(2,3-dimethylphenyl)-4-methyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F148-0506

Molecular Formula

C26H27N5O2 (C26 H27 N5 O2)

Compound Name

7-benzyl-N~3~-(2,3-dimethylphenyl)-4-methyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

IUPAC name

11-benzyl-N-(23-dimethylphenyl)-2-methyl-8-oxo-26711-tetraazatricyclo[7.4.0.0^{37}]trideca-1(9)35-triene-4-carboxamide

SMILES

Cc1cccc(NC(c(cnn23)c3N(C)C(CCN(Cc3ccccc3)C3)=C3C2=O)=O)c1C

InChI

InChI=1S/C26H27N5O2/c1-17-8-7-11-22(18(17)2)28-24(32)20-14-27-31-25(20)29(3)23-12-13-30(16-21(23)26(31)33)15-19-9-5-4-6-10-19/h4-11,14H,12-13,15-16H2,1-3H3,(H,28,32)

InChI Key

PJDUZONTWBVZNU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27104905

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

441.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.978

Distribution Coefficient, logD

3.976

Water Solubility, LogSw

-4.02

Polar Surface Area

54.577

Acid Dissociation Constant (pKa)

11.08

Base Dissociation Constant (pKb)

4.82

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

F148-0506 in Drug Discovery

Included in Screening Libraries

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F148-0506 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F148-0506?
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What is the minimum amount of F148-0506 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F148-0506
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F148-0506
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F148-0506 available by request