F148-0528 Screening compound: 7-benzyl-4-methyl-3-{[4-(2-pyridyl)piperazino]carbonyl}-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one

F148-0528 Screening compound: 7-benzyl-4-methyl-3-{[4-(2-pyridyl)piperazino]carbonyl}-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one
F148-0528 Screening compound: 7-benzyl-4-methyl-3-{[4-(2-pyridyl)piperazino]carbonyl}-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F148-0528
7-benzyl-4-methyl-3-{[4-(2-pyridyl)piperazino]carbonyl}-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F148-0528

Molecular Formula

C27H29N7O2 (C27 H29 N7 O2)

Compound Name

7-benzyl-4-methyl-3-{[4-(2-pyridyl)piperazino]carbonyl}-5,6,7,8-tetrahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidin-9(4H)-one

IUPAC name

11-benzyl-2-methyl-4-[4-(pyridin-2-yl)piperazine-1-carbonyl]-26711-tetraazatricyclo[7.4.0.0^{37}]trideca-1(9)35-trien-8-one

SMILES

CN(c(n1nc2)c2C(N(CC2)CCN2c2ncccc2)=O)C(CCN(Cc2ccccc2)C2)=C2C1=O

InChI

InChI=1S/C27H29N7O2/c1-30-23-10-12-31(18-20-7-3-2-4-8-20)19-22(23)27(36)34-25(30)21(17-29-34)26(35)33-15-13-32(14-16-33)24-9-5-6-11-28-24/h2-9,11,17H,10,12-16,18-19H2,1H3

InChI Key

NSBBZLWNMRRUNS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27104921

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

483.57

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

2.564

Distribution Coefficient, logD

2.555

Water Solubility, LogSw

-2.67

Polar Surface Area

60.603

Acid Dissociation Constant (pKa)

24.69

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

F148-0528 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

SmartTM Library (51161 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Epigenetics Focused Set (26518 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Ion Channels

References: we are preparing a list of scientific research reports with F148-0528 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F148-0528?
Check Price and Availability of F148-0528, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F148-0528 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F148-0528
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F148-0528
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F148-0528 available by request