F148-0578 Screening compound: 7-benzyl-4-methyl-9-oxo-N~3~-[3-(1-pyrrolidinylmethyl)phenyl]-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

F148-0578 Screening compound: 7-benzyl-4-methyl-9-oxo-N~3~-[3-(1-pyrrolidinylmethyl)phenyl]-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide
F148-0578 Screening compound: 7-benzyl-4-methyl-9-oxo-N~3~-[3-(1-pyrrolidinylmethyl)phenyl]-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F148-0578
7-benzyl-4-methyl-9-oxo-N~3~-[3-(1-pyrrolidinylmethyl)phenyl]-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F148-0578

Molecular Formula

C29H32N6O2 (C29 H32 N6 O2)

Compound Name

7-benzyl-4-methyl-9-oxo-N~3~-[3-(1-pyrrolidinylmethyl)phenyl]-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

IUPAC name

11-benzyl-2-methyl-8-oxo-N-{3-[(pyrrolidin-1-yl)methyl]phenyl}-26711-tetraazatricyclo[7.4.0.0^{37}]trideca-1(9)35-triene-4-carboxamide

SMILES

CN(c(n1nc2)c2C(Nc2cc(CN3CCCC3)ccc2)=O)C(CCN(Cc2ccccc2)C2)=C2C1=O

InChI

InChI=1S/C29H32N6O2/c1-32-26-12-15-34(18-21-8-3-2-4-9-21)20-25(26)29(37)35-28(32)24(17-30-35)27(36)31-23-11-7-10-22(16-23)19-33-13-5-6-14-33/h2-4,7-11,16-17H,5-6,12-15,18-20H2,1H3,(H,31,36)

InChI Key

LDEZOXWJDNPCDA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27104955

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.61

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.150

Distribution Coefficient, logD

0.301

Water Solubility, LogSw

-3.44

Polar Surface Area

59.373

Acid Dissociation Constant (pKa)

10.97

Base Dissociation Constant (pKb)

10.25

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.50

F148-0578 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F148-0578 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F148-0578?
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What is the minimum amount of F148-0578 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F148-0578
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F148-0578
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F148-0578 available by request