F148-0583 Screening compound: N~3~-(4-fluorobenzyl)-4,7-dimethyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

F148-0583 Screening compound: N~3~-(4-fluorobenzyl)-4,7-dimethyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide
F148-0583 Screening compound: N~3~-(4-fluorobenzyl)-4,7-dimethyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F148-0583
N~3~-(4-fluorobenzyl)-4,7-dimethyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F148-0583

Molecular Formula

C19H20FN5O2 (C19 H20 FN5 O2)

Compound Name

N~3~-(4-fluorobenzyl)-4,7-dimethyl-9-oxo-4,5,6,7,8,9-hexahydropyrazolo[1,5-a]pyrido[4,3-d]pyrimidine-3-carboxamide

IUPAC name

N-[(4-fluorophenyl)methyl]-211-dimethyl-8-oxo-26711-tetraazatricyclo[7.4.0.0^{37}]trideca-1(9)35-triene-4-carboxamide

SMILES

CN(CC1)CC(C(n2nc3)=O)=C1N(C)c2c3C(NCc(cc1)ccc1F)=O

InChI

InChI=1S/C19H20FN5O2/c1-23-8-7-16-15(11-23)19(27)25-18(24(16)2)14(10-22-25)17(26)21-9-12-3-5-13(20)6-4-12/h3-6,10H,7-9,11H2,1-2H3,(H,21,26)

InChI Key

AELMUVRASFYPAY-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27104956

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

369.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.402

Distribution Coefficient, logD

1.391

Water Solubility, LogSw

-2.29

Polar Surface Area

56.533

Acid Dissociation Constant (pKa)

11.21

Base Dissociation Constant (pKb)

5.80

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

31.60

F148-0583 in Drug Discovery

Included in Screening Libraries

Antifungal Library (16415 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Agro:
  • Agro
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F148-0583 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F148-0583?
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What is the minimum amount of F148-0583 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F148-0583
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F148-0583
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F148-0583 available by request