F154-0337 Screening compound: 4-{4-[(2-{[(2-chloro-4-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-c]pyridin-3-yl)methyl]benzoyl}morpholine

F154-0337 Screening compound: 4-{4-[(2-{[(2-chloro-4-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-c]pyridin-3-yl)methyl]benzoyl}morpholine
F154-0337 Screening compound: 4-{4-[(2-{[(2-chloro-4-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-c]pyridin-3-yl)methyl]benzoyl}morpholine alternative view

Chemical Structure Depiction of ChemDiv screening compound F154-0337
4-{4-[(2-{[(2-chloro-4-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-c]pyridin-3-yl)methyl]benzoyl}morpholine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F154-0337

Molecular Formula

C25H22ClFN4O2S (C25 H22 ClFN4 O2 S)

Compound Name

4-{4-[(2-{[(2-chloro-4-fluorophenyl)methyl]sulfanyl}-3H-imidazo[4,5-c]pyridin-3-yl)methyl]benzoyl}morpholine

IUPAC name

4-{4-[(2-{[(2-chloro-4-fluorophenyl)methyl]sulfanyl}-3H-imidazo[45-c]pyridin-3-yl)methyl]benzoyl}morpholine

SMILES

O=C(c1ccc(Cn2c(SCc(ccc(F)c3)c3Cl)nc3c2cncc3)cc1)N1CCOCC1

InChI

InChI=1S/C25H22ClFN4O2S/c26-21-13-20(27)6-5-19(21)16-34-25-29-22-7-8-28-14-23(22)31(25)15-17-1-3-18(4-2-17)24(32)30-9-11-33-12-10-30/h1-8,13-14H,9-12,15-16H2

InChI Key

LBGJDIINQXZAFA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27105971

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

496.99

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.494

Distribution Coefficient, logD

4.491

Water Solubility, LogSw

-4.55

Polar Surface Area

44.552

Acid Dissociation Constant (pKa)

22.95

Base Dissociation Constant (pKb)

5.26

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

F154-0337 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nucleic Acid Ligands (8311 compounds)

PI3K-Targeted Library (17255 compounds)

Developmental Pathway (Hh/Wnt) Set (2238 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Others

References: we are preparing a list of scientific research reports with F154-0337 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F154-0337?
Check Price and Availability of F154-0337, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F154-0337 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F154-0337
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F154-0337
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F154-0337 available by request