F159-0151 Screening compound: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]urea

F159-0151 Screening compound: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]urea
F159-0151 Screening compound: 1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound F159-0151
1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F159-0151

Molecular Formula

C23H24N4O4 (C23 H24 N4 O4)

Compound Name

1-(2,3-dihydro-1,4-benzodioxin-6-yl)-3-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]urea

IUPAC name

1-(23-dihydro-14-benzodioxin-6-yl)-3-[4-methyl-2-(morpholin-4-yl)quinolin-6-yl]urea

SMILES

Cc1c(cc(cc2)NC(Nc(cc3)cc4c3OCCO4)=O)c2nc(N2CCOCC2)c1

InChI

InChI=1S/C23H24N4O4/c1-15-12-22(27-6-8-29-9-7-27)26-19-4-2-16(13-18(15)19)24-23(28)25-17-3-5-20-21(14-17)31-11-10-30-20/h2-5,12-14H,6-11H2,1H3,(H2,24,25,28)

InChI Key

CPFYQDHAQKUYKZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943839

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

420.47

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.954

Distribution Coefficient, logD

3.953

Water Solubility, LogSw

-4.01

Polar Surface Area

67.520

Acid Dissociation Constant (pKa)

12.12

Base Dissociation Constant (pKb)

4.21

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

F159-0151 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F159-0151 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F159-0151?
Check Price and Availability of F159-0151, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F159-0151 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F159-0151
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F159-0151
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F159-0151 available by request