F160-1220 Screening compound: 5,6-dimethyl-3-{3-oxo-3-[4-(pyridin-2-yl)piperazin-1-yl]propyl}-3H,4H-furo[2,3-d]pyrimidin-4-one

F160-1220 Screening compound: 5,6-dimethyl-3-{3-oxo-3-[4-(pyridin-2-yl)piperazin-1-yl]propyl}-3H,4H-furo[2,3-d]pyrimidin-4-one
F160-1220 Screening compound: 5,6-dimethyl-3-{3-oxo-3-[4-(pyridin-2-yl)piperazin-1-yl]propyl}-3H,4H-furo[2,3-d]pyrimidin-4-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F160-1220
5,6-dimethyl-3-{3-oxo-3-[4-(pyridin-2-yl)piperazin-1-yl]propyl}-3H,4H-furo[2,3-d]pyrimidin-4-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F160-1220

Molecular Formula

C20H23N5O3 (C20 H23 N5 O3)

Compound Name

5,6-dimethyl-3-{3-oxo-3-[4-(pyridin-2-yl)piperazin-1-yl]propyl}-3H,4H-furo[2,3-d]pyrimidin-4-one

IUPAC name

56-dimethyl-3-{3-oxo-3-[4-(pyridin-2-yl)piperazin-1-yl]propyl}-3H4H-furo[23-d]pyrimidin-4-one

SMILES

Cc1c(C)oc(N=CN2CCC(N(CC3)CCN3c3ncccc3)=O)c1C2=O

InChI

InChI=1S/C20H23N5O3/c1-14-15(2)28-19-18(14)20(27)25(13-22-19)8-6-17(26)24-11-9-23(10-12-24)16-5-3-4-7-21-16/h3-5,7,13H,6,8-12H2,1-2H3

InChI Key

LGWPJVCVDPJDEV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27106289

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

381.43

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.302

Distribution Coefficient, logD

1.293

Water Solubility, LogSw

-1.58

Polar Surface Area

61.864

Acid Dissociation Constant (pKa)

23.94

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

40.00

F160-1220 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F160-1220 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F160-1220?
Check Price and Availability of F160-1220, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F160-1220 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F160-1220
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F160-1220
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F160-1220 available by request