F170-0017 Screening compound: 3-[2-(pyridin-3-yl)-1H-indol-3-yl]-1-[3-(trifluoromethyl)phenyl]urea

F170-0017 Screening compound: 3-[2-(pyridin-3-yl)-1H-indol-3-yl]-1-[3-(trifluoromethyl)phenyl]urea
F170-0017 Screening compound: 3-[2-(pyridin-3-yl)-1H-indol-3-yl]-1-[3-(trifluoromethyl)phenyl]urea alternative view

Chemical Structure Depiction of ChemDiv screening compound F170-0017
3-[2-(pyridin-3-yl)-1H-indol-3-yl]-1-[3-(trifluoromethyl)phenyl]urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F170-0017

Molecular Formula

C21H15F3N4O (C21 H15 F3 N4 O)

Compound Name

3-[2-(pyridin-3-yl)-1H-indol-3-yl]-1-[3-(trifluoromethyl)phenyl]urea

IUPAC name

3-[2-(pyridin-3-yl)-1H-indol-3-yl]-1-[3-(trifluoromethyl)phenyl]urea

SMILES

O=C(Nc1c(-c2cnccc2)[nH]c2c1cccc2)Nc1cccc(C(F)(F)F)c1

InChI

InChI=1S/C21H15F3N4O/c22-21(23,24)14-6-3-7-15(11-14)26-20(29)28-19-16-8-1-2-9-17(16)27-18(19)13-5-4-10-25-12-13/h1-12,27H,(H2,26,28,29)

InChI Key

RBQXMSXJVJEHIR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14943898

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

396.37

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.559

Distribution Coefficient, logD

4.559

Water Solubility, LogSw

-4.49

Polar Surface Area

50.512

Acid Dissociation Constant (pKa)

11.81

Base Dissociation Constant (pKb)

2.43

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

4.80

F170-0017 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F170-0017 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F170-0017?
Check Price and Availability of F170-0017, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F170-0017 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F170-0017
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F170-0017
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F170-0017 available by request