F177-0280 Screening compound: N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}-2-(3-phenyl-1,2,4-oxadiazol-5-yl)benzamide

F177-0280 Screening compound: N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}-2-(3-phenyl-1,2,4-oxadiazol-5-yl)benzamide
F177-0280 Screening compound: N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}-2-(3-phenyl-1,2,4-oxadiazol-5-yl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F177-0280
N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}-2-(3-phenyl-1,2,4-oxadiazol-5-yl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F177-0280

Molecular Formula

C27H26FN5O2 (C27 H26 FN5 O2)

Compound Name

N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}-2-(3-phenyl-1,2,4-oxadiazol-5-yl)benzamide

IUPAC name

N-{2-[4-(2-fluorophenyl)piperazin-1-yl]ethyl}-2-(3-phenyl-124-oxadiazol-5-yl)benzamide

SMILES

O=C(c(cccc1)c1-c1nc(-c2ccccc2)no1)NCCN(CC1)CCN1c(cccc1)c1F

InChI

InChI=1S/C27H26FN5O2/c28-23-12-6-7-13-24(23)33-18-16-32(17-19-33)15-14-29-26(34)21-10-4-5-11-22(21)27-30-25(31-35-27)20-8-2-1-3-9-20/h1-13H,14-19H2,(H,29,34)

InChI Key

POFLZLOZWZKKQH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107055

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.674

Distribution Coefficient, logD

4.664

Water Solubility, LogSw

-4.60

Polar Surface Area

62.841

Acid Dissociation Constant (pKa)

12.98

Base Dissociation Constant (pKb)

5.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

F177-0280 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system

References: we are preparing a list of scientific research reports with F177-0280 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F177-0280?
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What is the minimum amount of F177-0280 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F177-0280
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F177-0280
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F177-0280 available by request