F177-0917 Screening compound: 1-{2-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(pyridin-2-yl)piperazine

F177-0917 Screening compound: 1-{2-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(pyridin-2-yl)piperazine
F177-0917 Screening compound: 1-{2-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F177-0917
1-{2-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F177-0917

Molecular Formula

C24H20ClN5O2 (C24 H20 ClN5 O2)

Compound Name

1-{2-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(pyridin-2-yl)piperazine

IUPAC name

1-{2-[3-(4-chlorophenyl)-124-oxadiazol-5-yl]benzoyl}-4-(pyridin-2-yl)piperazine

SMILES

O=C(c(cccc1)c1-c1nc(-c(cc2)ccc2Cl)no1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C24H20ClN5O2/c25-18-10-8-17(9-11-18)22-27-23(32-28-22)19-5-1-2-6-20(19)24(31)30-15-13-29(14-16-30)21-7-3-4-12-26-21/h1-12H,13-16H2

InChI Key

OXZIRDVDQLBQMV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107074

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

445.91

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

5.046

Distribution Coefficient, logD

5.037

Water Solubility, LogSw

-5.28

Polar Surface Area

60.064

Acid Dissociation Constant (pKa)

24.69

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

F177-0917 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F177-0917 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F177-0917?
Check Price and Availability of F177-0917, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F177-0917 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F177-0917
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F177-0917
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F177-0917 available by request