F177-1194 Screening compound: N-(5-chloropyridin-2-yl)-2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide

F177-1194 Screening compound: N-(5-chloropyridin-2-yl)-2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide
F177-1194 Screening compound: N-(5-chloropyridin-2-yl)-2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F177-1194
N-(5-chloropyridin-2-yl)-2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F177-1194

Molecular Formula

C20H12ClFN4O2 (C20 H12 ClFN4 O2)

Compound Name

N-(5-chloropyridin-2-yl)-2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzamide

IUPAC name

N-(5-chloropyridin-2-yl)-2-[3-(4-fluorophenyl)-124-oxadiazol-5-yl]benzamide

SMILES

O=C(c(cccc1)c1-c1nc(-c(cc2)ccc2F)no1)Nc(cc1)ncc1Cl

InChI

InChI=1S/C20H12ClFN4O2/c21-13-7-10-17(23-11-13)24-19(27)15-3-1-2-4-16(15)20-25-18(26-28-20)12-5-8-14(22)9-6-12/h1-11H,(H,23,24,27)

InChI Key

YPTIYEXLOMTXTJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107088

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

394.79

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.331

Distribution Coefficient, logD

5.233

Water Solubility, LogSw

-5.94

Polar Surface Area

64.440

Acid Dissociation Constant (pKa)

8.00

Base Dissociation Constant (pKb)

0.39

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

F177-1194 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Type II Kinase Inhibitors Library (6956 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Hemic and lymphatic
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with F177-1194 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F177-1194?
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What is the minimum amount of F177-1194 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F177-1194
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F177-1194
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F177-1194 available by request