F177-1256 Screening compound: 2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(4-sulfamoylphenyl)benzamide

F177-1256 Screening compound: 2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(4-sulfamoylphenyl)benzamide
F177-1256 Screening compound: 2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(4-sulfamoylphenyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F177-1256
2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(4-sulfamoylphenyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F177-1256

Molecular Formula

C21H15FN4O4S (C21 H15 FN4 O4 S)

Compound Name

2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]-N-(4-sulfamoylphenyl)benzamide

IUPAC name

2-[3-(4-fluorophenyl)-124-oxadiazol-5-yl]-N-(4-sulfamoylphenyl)benzamide

SMILES

NS(c(cc1)ccc1NC(c(cccc1)c1-c1nc(-c(cc2)ccc2F)no1)=O)(=O)=O

InChI

InChI=1S/C21H15FN4O4S/c22-14-7-5-13(6-8-14)19-25-21(30-26-19)18-4-2-1-3-17(18)20(27)24-15-9-11-16(12-10-15)31(23,28)29/h1-12H,(H,24,27)(H2,23,28,29)

InChI Key

ZNSKNAADLNICDM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107099

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

438.44

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

3.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.224

Distribution Coefficient, logD

3.218

Water Solubility, LogSw

-4.03

Polar Surface Area

105.339

Acid Dissociation Constant (pKa)

9.26

Base Dissociation Constant (pKb)

-4.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

0.00

F177-1256 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Carbonic Anhydrase II Library (4939 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F177-1256 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F177-1256?
Check Price and Availability of F177-1256, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F177-1256 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F177-1256
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F177-1256
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F177-1256 available by request