F177-1344 Screening compound: 1-{2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(furan-2-carbonyl)piperazine

F177-1344 Screening compound: 1-{2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(furan-2-carbonyl)piperazine
F177-1344 Screening compound: 1-{2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(furan-2-carbonyl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F177-1344
1-{2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(furan-2-carbonyl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F177-1344

Molecular Formula

C24H19FN4O4 (C24 H19 FN4 O4)

Compound Name

1-{2-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]benzoyl}-4-(furan-2-carbonyl)piperazine

IUPAC name

1-{2-[3-(4-fluorophenyl)-124-oxadiazol-5-yl]benzoyl}-4-(furan-2-carbonyl)piperazine

SMILES

O=C(c1ccco1)N(CC1)CCN1C(c(cccc1)c1-c1nc(-c(cc2)ccc2F)no1)=O

InChI

InChI=1S/C24H19FN4O4/c25-17-9-7-16(8-10-17)21-26-22(33-27-21)18-4-1-2-5-19(18)23(30)28-11-13-29(14-12-28)24(31)20-6-3-15-32-20/h1-10,15H,11-14H2

InChI Key

JXEVCEKBUMGIPB-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD14944050

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

446.44

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.385

Distribution Coefficient, logD

3.385

Water Solubility, LogSw

-3.72

Polar Surface Area

73.327

Acid Dissociation Constant (pKa)

28.60

Base Dissociation Constant (pKb)

-3.95

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

F177-1344 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with F177-1344 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F177-1344?
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What is the minimum amount of F177-1344 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F177-1344
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F177-1344
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F177-1344 available by request