F180-0131 Screening compound: 1-[4-(3,5-dimethyl-1,2-oxazol-4-yl)benzenesulfonyl]-4-(pyridin-2-yl)piperazine

F180-0131 Screening compound: 1-[4-(3,5-dimethyl-1,2-oxazol-4-yl)benzenesulfonyl]-4-(pyridin-2-yl)piperazine
F180-0131 Screening compound: 1-[4-(3,5-dimethyl-1,2-oxazol-4-yl)benzenesulfonyl]-4-(pyridin-2-yl)piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F180-0131
1-[4-(3,5-dimethyl-1,2-oxazol-4-yl)benzenesulfonyl]-4-(pyridin-2-yl)piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F180-0131

Molecular Formula

C20H22N4O3S (C20 H22 N4 O3 S)

Compound Name

1-[4-(3,5-dimethyl-1,2-oxazol-4-yl)benzenesulfonyl]-4-(pyridin-2-yl)piperazine

IUPAC name

1-[4-(35-dimethyl-12-oxazol-4-yl)benzenesulfonyl]-4-(pyridin-2-yl)piperazine

SMILES

Cc1noc(C)c1-c(cc1)ccc1S(N(CC1)CCN1c1ncccc1)(=O)=O

InChI

InChI=1S/C20H22N4O3S/c1-15-20(16(2)27-22-15)17-6-8-18(9-7-17)28(25,26)24-13-11-23(12-14-24)19-5-3-4-10-21-19/h3-10H,11-14H2,1-2H3

InChI Key

QKVXEXNBEHYZKR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107176

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.49

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.206

Distribution Coefficient, logD

3.182

Water Solubility, LogSw

-3.50

Polar Surface Area

65.488

Acid Dissociation Constant (pKa)

24.57

Base Dissociation Constant (pKb)

6.16

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.00

F180-0131 in Drug Discovery

Included in Screening Libraries

SmartTM Library (51161 compounds)

Akt-Targeted Library (14764 compounds)

Epigenetics Focused Set (26518 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F180-0131 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F180-0131?
Check Price and Availability of F180-0131, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F180-0131 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F180-0131
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F180-0131
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F180-0131 available by request