F182-0147 Screening compound: 8-[6-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridazin-3-yl]-1,4-dioxa-8-azaspiro[4.5]decane

F182-0147 Screening compound: 8-[6-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridazin-3-yl]-1,4-dioxa-8-azaspiro[4.5]decane
F182-0147 Screening compound: 8-[6-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridazin-3-yl]-1,4-dioxa-8-azaspiro[4.5]decane alternative view

Chemical Structure Depiction of ChemDiv screening compound F182-0147
8-[6-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridazin-3-yl]-1,4-dioxa-8-azaspiro[4.5]decane

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F182-0147

Molecular Formula

C19H19N5O3 (C19 H19 N5 O3)

Compound Name

8-[6-(3-phenyl-1,2,4-oxadiazol-5-yl)pyridazin-3-yl]-1,4-dioxa-8-azaspiro[4.5]decane

IUPAC name

8-[6-(3-phenyl-124-oxadiazol-5-yl)pyridazin-3-yl]-14-dioxa-8-azaspiro[4.5]decane

SMILES

C1OC(CC2)(CCN2c(cc2)nnc2-c2nc(-c3ccccc3)no2)OC1

InChI

InChI=1S/C19H19N5O3/c1-2-4-14(5-3-1)17-20-18(27-23-17)15-6-7-16(22-21-15)24-10-8-19(9-11-24)25-12-13-26-19/h1-7H,8-13H2

InChI Key

HMJWZDJTHAPSFF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107259

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

365.39

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.833

Distribution Coefficient, logD

2.833

Water Solubility, LogSw

-3.00

Polar Surface Area

70.740

Acid Dissociation Constant (pKa)

24.76

Base Dissociation Constant (pKb)

3.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.80

F182-0147 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
Agro:
  • Agro

References: we are preparing a list of scientific research reports with F182-0147 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F182-0147?
Check Price and Availability of F182-0147, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F182-0147 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F182-0147
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F182-0147
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F182-0147 available by request