F182-0400 Screening compound: N-(2,4-dimethoxyphenyl)-6-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-amine

F182-0400 Screening compound: N-(2,4-dimethoxyphenyl)-6-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-amine
F182-0400 Screening compound: N-(2,4-dimethoxyphenyl)-6-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound F182-0400
N-(2,4-dimethoxyphenyl)-6-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F182-0400

Molecular Formula

C21H19N5O3 (C21 H19 N5 O3)

Compound Name

N-(2,4-dimethoxyphenyl)-6-[3-(4-methylphenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-amine

IUPAC name

N-(24-dimethoxyphenyl)-6-[3-(4-methylphenyl)-124-oxadiazol-5-yl]pyridazin-3-amine

SMILES

Cc(cc1)ccc1-c1noc(-c(cc2)nnc2Nc(ccc(OC)c2)c2OC)n1

InChI

InChI=1S/C21H19N5O3/c1-13-4-6-14(7-5-13)20-23-21(29-26-20)17-10-11-19(25-24-17)22-16-9-8-15(27-2)12-18(16)28-3/h4-12H,1-3H3,(H,22,25)

InChI Key

RUNBPJXEUHEDKM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107284

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.41

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.805

Distribution Coefficient, logD

4.791

Water Solubility, LogSw

-4.61

Polar Surface Area

77.343

Acid Dissociation Constant (pKa)

17.98

Base Dissociation Constant (pKb)

5.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

14.30

F182-0400 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F182-0400 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F182-0400?
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What is the minimum amount of F182-0400 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F182-0400
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F182-0400
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F182-0400 available by request