F182-0899 Screening compound: 6-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(oxolan-2-yl)methyl]pyridazin-3-amine

F182-0899 Screening compound: 6-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(oxolan-2-yl)methyl]pyridazin-3-amine
F182-0899 Screening compound: 6-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(oxolan-2-yl)methyl]pyridazin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound F182-0899
6-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(oxolan-2-yl)methyl]pyridazin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F182-0899

Molecular Formula

C17H16ClN5O2 (C17 H16 ClN5 O2)

Compound Name

6-[3-(4-chlorophenyl)-1,2,4-oxadiazol-5-yl]-N-[(oxolan-2-yl)methyl]pyridazin-3-amine

IUPAC name

6-[3-(4-chlorophenyl)-124-oxadiazol-5-yl]-N-[(oxolan-2-yl)methyl]pyridazin-3-amine

SMILES

Clc(cc1)ccc1-c1noc(-c(cc2)nnc2NCC2OCCC2)n1

InChI

InChI=1S/C17H16ClN5O2/c18-12-5-3-11(4-6-12)16-20-17(25-23-16)14-7-8-15(22-21-14)19-10-13-2-1-9-24-13/h3-8,13H,1-2,9-10H2,(H,19,22)/t13-/m1/s1

InChI Key

JNMSTIMVKRRYPU-CYBMUJFWSA-N

MDL Number (MFCD)

MFCD27107328

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

357.8

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.298

Distribution Coefficient, logD

3.298

Water Solubility, LogSw

-3.93

Polar Surface Area

72.843

Acid Dissociation Constant (pKa)

19.26

Base Dissociation Constant (pKb)

3.08

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

29.40

F182-0899 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • Kinases
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F182-0899 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F182-0899?
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What is the minimum amount of F182-0899 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F182-0899
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F182-0899
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F182-0899 available by request