F182-1278 Screening compound: N-[2-(diethylamino)ethyl]-6-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-amine

F182-1278 Screening compound: N-[2-(diethylamino)ethyl]-6-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-amine
F182-1278 Screening compound: N-[2-(diethylamino)ethyl]-6-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound F182-1278
N-[2-(diethylamino)ethyl]-6-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F182-1278

Molecular Formula

C18H21FN6O (C18 H21 FN6 O)

Compound Name

N-[2-(diethylamino)ethyl]-6-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-amine

IUPAC name

N-[2-(diethylamino)ethyl]-6-[3-(4-fluorophenyl)-124-oxadiazol-5-yl]pyridazin-3-amine

SMILES

CCN(CC)CCNc(cc1)nnc1-c1nc(-c(cc2)ccc2F)no1

InChI

InChI=1S/C18H21FN6O/c1-3-25(4-2)12-11-20-16-10-9-15(22-23-16)18-21-17(24-26-18)13-5-7-14(19)8-6-13/h5-10H,3-4,11-12H2,1-2H3,(H,20,23)

InChI Key

ZWGZQJSFPQNSSV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107375

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

356.4

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.421

Distribution Coefficient, logD

1.334

Water Solubility, LogSw

-3.35

Polar Surface Area

67.713

Acid Dissociation Constant (pKa)

18.86

Base Dissociation Constant (pKb)

9.48

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

F182-1278 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

Anticancer Library (62698 compounds)

Antiviral Library (67538 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Cancer
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with F182-1278 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F182-1278?
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What is the minimum amount of F182-1278 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F182-1278
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F182-1278
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F182-1278 available by request