F182-1407 Screening compound: 3-[3-(2,5-dimethoxyphenyl)pyrrolidin-1-yl]-6-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridazine

F182-1407 Screening compound: 3-[3-(2,5-dimethoxyphenyl)pyrrolidin-1-yl]-6-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridazine
F182-1407 Screening compound: 3-[3-(2,5-dimethoxyphenyl)pyrrolidin-1-yl]-6-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F182-1407
3-[3-(2,5-dimethoxyphenyl)pyrrolidin-1-yl]-6-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F182-1407

Molecular Formula

C24H22FN5O3 (C24 H22 FN5 O3)

Compound Name

3-[3-(2,5-dimethoxyphenyl)pyrrolidin-1-yl]-6-[3-(4-fluorophenyl)-1,2,4-oxadiazol-5-yl]pyridazine

IUPAC name

3-[3-(25-dimethoxyphenyl)pyrrolidin-1-yl]-6-[3-(4-fluorophenyl)-124-oxadiazol-5-yl]pyridazine

SMILES

COc(cc1)cc(C(CC2)CN2c(cc2)nnc2-c2nc(-c(cc3)ccc3F)no2)c1OC

InChI

InChI=1S/C24H22FN5O3/c1-31-18-7-9-21(32-2)19(13-18)16-11-12-30(14-16)22-10-8-20(27-28-22)24-26-23(29-33-24)15-3-5-17(25)6-4-15/h3-10,13,16H,11-12,14H2,1-2H3/t16-/m1/s1

InChI Key

VOWYFHVUFPEQDA-MRXNPFEDSA-N

MDL Number (MFCD)

MFCD27107396

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

447.47

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.032

Distribution Coefficient, logD

5.032

Water Solubility, LogSw

-4.79

Polar Surface Area

71.505

Acid Dissociation Constant (pKa)

20.56

Base Dissociation Constant (pKb)

2.37

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

25.00

F182-1407 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Targeted Diversity Library (40567 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
Agro:
  • Agro

References: we are preparing a list of scientific research reports with F182-1407 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F182-1407?
Check Price and Availability of F182-1407, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F182-1407 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F182-1407
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F182-1407
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F182-1407 available by request