F182-2373 Screening compound: 1-{6-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-yl}-N-(4-methoxyphenyl)piperidine-4-carboxamide

F182-2373 Screening compound: 1-{6-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-yl}-N-(4-methoxyphenyl)piperidine-4-carboxamide
F182-2373 Screening compound: 1-{6-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-yl}-N-(4-methoxyphenyl)piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F182-2373
1-{6-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-yl}-N-(4-methoxyphenyl)piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F182-2373

Molecular Formula

C25H23ClN6O3 (C25 H23 ClN6 O3)

Compound Name

1-{6-[3-(3-chlorophenyl)-1,2,4-oxadiazol-5-yl]pyridazin-3-yl}-N-(4-methoxyphenyl)piperidine-4-carboxamide

IUPAC name

1-{6-[3-(3-chlorophenyl)-124-oxadiazol-5-yl]pyridazin-3-yl}-N-(4-methoxyphenyl)piperidine-4-carboxamide

SMILES

COc(cc1)ccc1NC(C(CC1)CCN1c(cc1)nnc1-c1nc(-c2cccc(Cl)c2)no1)=O

InChI

InChI=1S/C25H23ClN6O3/c1-34-20-7-5-19(6-8-20)27-24(33)16-11-13-32(14-12-16)22-10-9-21(29-30-22)25-28-23(31-35-25)17-3-2-4-18(26)15-17/h2-10,15-16H,11-14H2,1H3,(H,27,33)

InChI Key

XLOUJJMTRRPHMU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107413

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

490.95

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

4.834

Distribution Coefficient, logD

4.834

Water Solubility, LogSw

-4.92

Polar Surface Area

86.938

Acid Dissociation Constant (pKa)

11.75

Base Dissociation Constant (pKb)

3.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

F182-2373 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Macl-GPIb alpha Interaction Library (22969 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Protein Tyrosine Phosphatase Non-receptor Type (PTPN) Targeted Library (32556 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Hemic and lymphatic
  • Cardiovascular
  • Cancer
  • Nervous system
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Endocrine
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics
Targets:
  • Phosphatases

References: we are preparing a list of scientific research reports with F182-2373 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F182-2373?
Check Price and Availability of F182-2373, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F182-2373 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F182-2373
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F182-2373
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F182-2373 available by request