F182-3278 Screening compound: 3-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}-6-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyridazine

F182-3278 Screening compound: 3-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}-6-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyridazine
F182-3278 Screening compound: 3-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}-6-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyridazine alternative view

Chemical Structure Depiction of ChemDiv screening compound F182-3278
3-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}-6-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyridazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F182-3278

Molecular Formula

C25H24N6O4 (C25 H24 N6 O4)

Compound Name

3-{4-[(2H-1,3-benzodioxol-5-yl)methyl]piperazin-1-yl}-6-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]pyridazine

IUPAC name

3-{4-[(2H-13-benzodioxol-5-yl)methyl]piperazin-1-yl}-6-[3-(4-methoxyphenyl)-124-oxadiazol-5-yl]pyridazine

SMILES

COc(cc1)ccc1-c1noc(-c(cc2)nnc2N2CCN(Cc(cc3)cc4c3OCO4)CC2)n1

InChI

InChI=1S/C25H24N6O4/c1-32-19-5-3-18(4-6-19)24-26-25(35-29-24)20-7-9-23(28-27-20)31-12-10-30(11-13-31)15-17-2-8-21-22(14-17)34-16-33-21/h2-9,14H,10-13,15-16H2,1H3

InChI Key

QEWARYZRINHGII-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107472

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

472.5

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

4.045

Distribution Coefficient, logD

3.318

Water Solubility, LogSw

-4.17

Polar Surface Area

84.503

Acid Dissociation Constant (pKa)

24.26

Base Dissociation Constant (pKb)

8.04

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

28.00

F182-3278 in Drug Discovery

Included in Screening Libraries

Anti-infective Library (19449 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Immune system
  • animal
Mechanism of action:
  • PPI modulators

References: we are preparing a list of scientific research reports with F182-3278 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F182-3278?
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What is the minimum amount of F182-3278 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F182-3278
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F182-3278
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F182-3278 available by request