F184-0062 Screening compound: 7-{[3-(2,3-dihydro-1H-indole-1-carbonyl)piperidin-1-yl]sulfonyl}-6-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one

F184-0062 Screening compound: 7-{[3-(2,3-dihydro-1H-indole-1-carbonyl)piperidin-1-yl]sulfonyl}-6-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one
F184-0062 Screening compound: 7-{[3-(2,3-dihydro-1H-indole-1-carbonyl)piperidin-1-yl]sulfonyl}-6-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F184-0062
7-{[3-(2,3-dihydro-1H-indole-1-carbonyl)piperidin-1-yl]sulfonyl}-6-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F184-0062

Molecular Formula

C23H25N3O5S (C23 H25 N3 O5 S)

Compound Name

7-{[3-(2,3-dihydro-1H-indole-1-carbonyl)piperidin-1-yl]sulfonyl}-6-methyl-3,4-dihydro-2H-1,4-benzoxazin-3-one

IUPAC name

7-{[3-(23-dihydro-1H-indole-1-carbonyl)piperidin-1-yl]sulfonyl}-6-methyl-34-dihydro-2H-14-benzoxazin-3-one

SMILES

Cc(cc(c(OC1)c2)NC1=O)c2S(N(CCC1)CC1C(N(CC1)c2c1cccc2)=O)(=O)=O

InChI

InChI=1S/C23H25N3O5S/c1-15-11-18-20(31-14-22(27)24-18)12-21(15)32(29,30)25-9-4-6-17(13-25)23(28)26-10-8-16-5-2-3-7-19(16)26/h2-3,5,7,11-12,17H,4,6,8-10,13-14H2,1H3,(H,24,27)/t17-/m0/s1

InChI Key

XIEAJUHHZSZFHP-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD27107541

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.53

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.024

Distribution Coefficient, logD

2.024

Water Solubility, LogSw

-2.72

Polar Surface Area

80.832

Acid Dissociation Constant (pKa)

10.30

Base Dissociation Constant (pKb)

-0.78

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

39.10

F184-0062 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Kinases
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F184-0062 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F184-0062?
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What is the minimum amount of F184-0062 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F184-0062
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F184-0062
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F184-0062 available by request