F184-0353 Screening compound: 6-methyl-7-{[3-(3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carbonyl)piperidin-1-yl]sulfonyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one

F184-0353 Screening compound: 6-methyl-7-{[3-(3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carbonyl)piperidin-1-yl]sulfonyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one
F184-0353 Screening compound: 6-methyl-7-{[3-(3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carbonyl)piperidin-1-yl]sulfonyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one alternative view

Chemical Structure Depiction of ChemDiv screening compound F184-0353
6-methyl-7-{[3-(3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carbonyl)piperidin-1-yl]sulfonyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F184-0353

Molecular Formula

C23H24N4O6S (C23 H24 N4 O6 S)

Compound Name

6-methyl-7-{[3-(3-oxo-1,2,3,4-tetrahydroquinoxaline-1-carbonyl)piperidin-1-yl]sulfonyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one

IUPAC name

6-methyl-7-{[3-(3-oxo-1234-tetrahydroquinoxaline-1-carbonyl)piperidin-1-yl]sulfonyl}-34-dihydro-2H-14-benzoxazin-3-one

SMILES

Cc(cc(c(OC1)c2)NC1=O)c2S(N(CCC1)CC1C(N(C1)c(cccc2)c2NC1=O)=O)(=O)=O

InChI

InChI=1S/C23H24N4O6S/c1-14-9-17-19(33-13-22(29)25-17)10-20(14)34(31,32)26-8-4-5-15(11-26)23(30)27-12-21(28)24-16-6-2-3-7-18(16)27/h2-3,6-7,9-10,15H,4-5,8,11-13H2,1H3,(H,24,28)(H,25,29)/t15-/m0/s1

InChI Key

QJBKJLQIAIVESX-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD27107643

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

484.53

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

0.993

Distribution Coefficient, logD

0.992

Water Solubility, LogSw

-2.53

Polar Surface Area

105.299

Acid Dissociation Constant (pKa)

9.91

Base Dissociation Constant (pKb)

-1.26

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

34.80

F184-0353 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Mechanism of action:
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
Targets:
  • Others

References: we are preparing a list of scientific research reports with F184-0353 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F184-0353?
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What is the minimum amount of F184-0353 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F184-0353
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F184-0353
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F184-0353 available by request