F184-0484 Screening compound: 1-[(6-chloro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]-N-(3-chloro-4-methylphenyl)piperidine-3-carboxamide

F184-0484 Screening compound: 1-[(6-chloro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]-N-(3-chloro-4-methylphenyl)piperidine-3-carboxamide
F184-0484 Screening compound: 1-[(6-chloro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]-N-(3-chloro-4-methylphenyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F184-0484
1-[(6-chloro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]-N-(3-chloro-4-methylphenyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F184-0484

Molecular Formula

C21H21Cl2N3O5S (C21 H21 Cl2 N3 O5 S)

Compound Name

1-[(6-chloro-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]-N-(3-chloro-4-methylphenyl)piperidine-3-carboxamide

IUPAC name

1-[(6-chloro-3-oxo-34-dihydro-2H-14-benzoxazin-7-yl)sulfonyl]-N-(3-chloro-4-methylphenyl)piperidine-3-carboxamide

SMILES

Cc(ccc(NC(C(CCC1)CN1S(c(cc(c(N1)c2)OCC1=O)c2Cl)(=O)=O)=O)c1)c1Cl

InChI

InChI=1S/C21H21Cl2N3O5S/c1-12-4-5-14(7-15(12)22)24-21(28)13-3-2-6-26(10-13)32(29,30)19-9-18-17(8-16(19)23)25-20(27)11-31-18/h4-5,7-9,13H,2-3,6,10-11H2,1H3,(H,24,28)(H,25,27)/t13-/m0/s1

InChI Key

MXHJBQJURDXBIQ-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD27107668

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

498.39

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.341

Distribution Coefficient, logD

3.282

Water Solubility, LogSw

-3.64

Polar Surface Area

88.244

Acid Dissociation Constant (pKa)

8.24

Base Dissociation Constant (pKb)

-0.66

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

33.30

F184-0484 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F184-0484 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F184-0484?
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What is the minimum amount of F184-0484 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F184-0484
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F184-0484
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F184-0484 available by request