F184-1631 Screening compound: N-(4-bromo-2-fluorophenyl)-1-[(2,6-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]piperidine-3-carboxamide

F184-1631 Screening compound: N-(4-bromo-2-fluorophenyl)-1-[(2,6-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]piperidine-3-carboxamide
F184-1631 Screening compound: N-(4-bromo-2-fluorophenyl)-1-[(2,6-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F184-1631
N-(4-bromo-2-fluorophenyl)-1-[(2,6-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F184-1631

Molecular Formula

C22H23BrFN3O5S (C22 H23 BrFN3 O5 S)

Compound Name

N-(4-bromo-2-fluorophenyl)-1-[(2,6-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]piperidine-3-carboxamide

IUPAC name

N-(4-bromo-2-fluorophenyl)-1-[(26-dimethyl-3-oxo-34-dihydro-2H-14-benzoxazin-7-yl)sulfonyl]piperidine-3-carboxamide

SMILES

CC1Oc2cc(S(N(CCC3)CC3C(Nc(ccc(Br)c3)c3F)=O)(=O)=O)c(C)cc2NC1=O

InChI

InChI=1S/C22H23BrFN3O5S/c1-12-8-18-19(32-13(2)21(28)26-18)10-20(12)33(30,31)27-7-3-4-14(11-27)22(29)25-17-6-5-15(23)9-16(17)24/h5-6,8-10,13-14H,3-4,7,11H2,1-2H3,(H,25,29)(H,26,28)

InChI Key

VFAAGNIEKCHGOZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107710

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

540.41

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.256

Distribution Coefficient, logD

3.103

Water Solubility, LogSw

-3.47

Polar Surface Area

86.885

Acid Dissociation Constant (pKa)

7.77

Base Dissociation Constant (pKb)

-2.40

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

36.40

F184-1631 in Drug Discovery

Included in Screening Libraries

Protein Arginine Methyltransferases Library (27925 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with F184-1631 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F184-1631?
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What is the minimum amount of F184-1631 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F184-1631
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F184-1631
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F184-1631 available by request