F184-1646 Screening compound: 1-[(2,6-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]-N-(2,4-dimethylphenyl)piperidine-3-carboxamide

F184-1646 Screening compound: 1-[(2,6-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]-N-(2,4-dimethylphenyl)piperidine-3-carboxamide
F184-1646 Screening compound: 1-[(2,6-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]-N-(2,4-dimethylphenyl)piperidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound F184-1646
1-[(2,6-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]-N-(2,4-dimethylphenyl)piperidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

F184-1646

Molecular Formula

C24H29N3O5S (C24 H29 N3 O5 S)

Compound Name

1-[(2,6-dimethyl-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-7-yl)sulfonyl]-N-(2,4-dimethylphenyl)piperidine-3-carboxamide

IUPAC name

1-[(26-dimethyl-3-oxo-34-dihydro-2H-14-benzoxazin-7-yl)sulfonyl]-N-(24-dimethylphenyl)piperidine-3-carboxamide

SMILES

CC1Oc2cc(S(N(CCC3)CC3C(Nc3c(C)cc(C)cc3)=O)(=O)=O)c(C)cc2NC1=O

InChI

InChI=1S/C24H29N3O5S/c1-14-7-8-19(15(2)10-14)25-24(29)18-6-5-9-27(13-18)33(30,31)22-12-21-20(11-16(22)3)26-23(28)17(4)32-21/h7-8,10-12,17-18H,5-6,9,13H2,1-4H3,(H,25,29)(H,26,28)

InChI Key

DMOUTKRTHNZDSG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27107721

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

471.58

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.058

Distribution Coefficient, logD

3.058

Water Solubility, LogSw

-3.19

Polar Surface Area

86.885

Acid Dissociation Constant (pKa)

10.22

Base Dissociation Constant (pKb)

-0.13

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

41.70

F184-1646 in Drug Discovery

Included in Screening Libraries

PPI Inhibitors Tripeptide Mimetics (23972 compounds)

Protein Arginine Methyltransferases Library (27925 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • Epigenetic
  • PPI modulators
Structure:
  • Mimetics
  • Mimetics
Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Metabolic
Targets:
  • Others

References: we are preparing a list of scientific research reports with F184-1646 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound F184-1646?
Check Price and Availability of F184-1646, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of F184-1646 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for F184-1646
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for F184-1646
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of F184-1646 available by request